The show presents itself as a special 50th Anniversary episode, hosted by Pat Dudley (Tom Kenny). Tim and Eric haven't spoken since an unfortunate stairway incident, adding tension to the celebration. Featured segments include: Pierre teaching children how to meditate in a new instructional video; E-Z Kreme, a diarrhea-inducing product that helps you miss important events (spokesmanned by Bob Odenkirk); Richard Dunn's improvisation workshop, Dunn-Prov; the Cinco MIDI Organizer Filing System, which organizes MIDI files by date, kind, size, and name; and a live performance by Grum of 'Crackers and Snacks'.