| Security Guard | 0 |
| Self | 1 |
| Self - Musician | 1 |
| Senator Howell Tankerbell | 1 |
| Sensei Doug Duggart | 1 |
| Shana | 1 |
| Shanice | 1 |
| Shaquille O'Neal | 1 |
| Sharon Osbourne | 1 |
| Sheila Carter | 1 |
| Sheila E. | 1 |
| Sheldon Whitehouse | 1 |
| Shermy | 1 |
| Show Producer | 1 |
| Silky Johnson | 1 |
| Simon | 3 |
| Sinbad | 1 |
| Sir Bedevere the Wise | 1 |
| Sissy | 1 |
| Snoopy | 1 |
| Soldier 1 | 1 |
| Soldier 2 | 1 |
| Soldier 3 | 1 |
| Soldier 4 | 1 |
| Son | 2 |
| Spagett | 1 |
| Sports Pundit | 1 |
| Spud | 1 |
| Stan Schmenge | 1 |
| Starlett O'Hara | 1 |
| Statler | 1 |
| Stefon | 2 |
| Stephen Miller | 1 |
| Steve Jobs | 1 |
| Steve Urkel | 1 |
| Steward | 1 |
| Stewardess | 1 |
| Store Clerk | 1 |
| Stu | 1 |
| Stuart | 1 |
| Stuart Larkin | 5 |
| Stuart Smalley | 2 |
| Student | 1 |
| Student 1 | 1 |
| Sumbrella | 1 |
| Sump'n Claus | 1 |
| Superman | 1 |
| Sweetie Pie Jonus | 1 |
| Tairy Greene | 2 |
| Tauriel | 1 |
